Here is C#/VB.NET code that shows how to load image from TIFF file, annotate image, save annotated image to a new TIFF file: 
private static void AnnotateTiffUsingTemporaryFile()
{
    // create image collection
    Vintasoft.Imaging.ImageCollection images = new Vintasoft.Imaging.ImageCollection();
    // create annotation controller associated with image collection
    Vintasoft.Imaging.Annotation.AnnotationDataController annotations = 
        new Vintasoft.Imaging.Annotation.AnnotationDataController(images);
    // load TIFF file into collection
    images.Add("sourceTiffFile.tif");

    // get annotation collection for selected image
    Vintasoft.Imaging.Annotation.AnnotationDataCollection imageAnnotations = annotations[images.Count - 1];
    // create new annotation
    Vintasoft.Imaging.Annotation.RectangleAnnotationData anno = 
        new Vintasoft.Imaging.Annotation.RectangleAnnotationData();
    anno.Size = new System.Drawing.SizeF(300, 300);
    anno.FillBrush = new Vintasoft.Imaging.Annotation.AnnotationSolidBrush(System.Drawing.Color.AliceBlue);
    anno.Location = new System.Drawing.PointF(0, 0);
    // add new annotation into annotation collection
    imageAnnotations.Add(anno);

    Vintasoft.Imaging.Codecs.Encoders.TiffEncoder encoder = 
        new Vintasoft.Imaging.Codecs.Encoders.TiffEncoder();
    // specify that annotations must be saved with image collection
    encoder.AnnotationsFormat = Vintasoft.Imaging.AnnotationsFormat.VintasoftBinary;
    // save image collection synchronously to new file
    images.SaveSync("destTiffFile.tif", encoder);
}